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2016年4月24日星期日

Clemencia Aguinaldo’s story

On December 12, 2015, Ms. Clemencia from Philippine looks great in the khaki’s woolen coat. Before she was discharged, she and her daughter shook hands with Dr. Niu Lizhi, president of Fuda Cancer Hospital in farewell. She said gratefully, “I would like to express my sincere appreciation to Dr. Niu, without whom I might be still tortured by cancer...” Liu Hongyun, head of the nursing group of third ward found it even harder to say goodbye to them. She embraced them tightly and sent her best wishes. The scene was really moving.

A photo of the patient (in the middle) and medical workers
Clemencia is 69 years old this year. She told the reporter that she had always been in good health until July 2010 when she found a mass in the right lower neck. She received examination at a local hospital and was found to have right undifferentiated nasopharyngeal carcinoma. Her condition showed no remission after operation and daily treatment. Later on, a fellow townsman told her that Guangzhou Fuda Cancer Hospital in China has been delivering good therapeutic effects for patients and many people have sought treatment over there. Clemecia decided to give it a try for fear that her condition would aggravate.

In September 2010, she headed for Guangzhou Fuda Cancer Hospital with her daughter. She was surprised to learn that medical workers at FUDA should have arranged airport pick-up service for them. Clemecia said, “FUDA has been very considerate in taking care of foreign patients.”

With the assistance of medical workers at FUDA, Clemencia went through admission formalities in no time. Patient completed relevant examinations after admission. The admitting diagnosis was “multiple solid masses are detected in right neck, which were considered to be enlarged lymph nodes; nasopharyngeal carcinoma with lymph node metastases in right neck; right thyroid nodule.” The expert medical team led by Dr. Niu Lizhi discussed and finalized the treatment plan as argon-helium cryosurgery for her on the basis of the examination result.

Dr. Niu Lizhi introduced that Guangzhou Fuda Cancer Hospital became the first hospital in mainland China to have introduced argon-helium cryosurgery since its initiation in 2001. The biggest advantages of argon-helium cryosurgery lie in its complete destruction of tumor, prevention of tumor metastases, painless treatment process and exemption of body trauma.

Clemencia showed great satisfaction to the treatment plan and her willingness to cooperate with treatment.

On September 15, 2010, Clemencia underwent argon-helium cryosurgery at Guangzhou Fuda Cancer Hospital. She felt much better after the procedure. She also underwent two cycles of interventional chemotherapy on October 12 and November 1 respectively. She showed improved condition and was discharged.

Later, Clemencia underwent another three cycles of interventional chemotherapy at Fuda Cancer Hospital on December 2010, January 2011, and February 2011 respectively.

After she went back to Philippine, Clemencia received many times of examinations at local hospital and no evidence of tumor recurrence was ever found. Some of her friends were so surprised to see her in such good condition, saying, “You look so energetic and doesn’t look like a cancer patient at all”. Clemencia was really glad to hear that. She said her condition has improved significantly and she is totally fit after treatment at Fuda Cancer Hospital.

In December 2015, Clemencia come back to FUDA once again for re-examination and DC-CIK immunotherapy. She told the reporter that she now has good quality of sleep and good spirit every day. And she has resumed her living habit before she got sick. She takes a walk every day as walking is her favorite sport. She once again expressed her thanks to medical workers at FUDA for helping her regain a healthy life.

A photo of (from left to right) the patient’s daughter, the patient, Liu Hongyun, head of the nursing group of third ward, the patient’s husband (during hospitalization) 
A photo of (from left to right) the patient, patient’s daughter, Liu Hongyun, head of the nursing group of third ward on December 12, 2015

A photo of (from Left to right) the patient, patient’s daughter, Liu Hongyun, head of nursing group of third ward on December 12, 2015

TIPS:

Cryosurgical Ablation (CSA)

As a new treatment for cancer, cryosurgery has been approved by the United States FDA (Food and Drug Administration in 1998 and China FDA in 1999 respectively. China has been taking a lead in the world both in terms of cryosurgery cases and treated types of cancer. Since the introduction of cryosurgery in 2000, Fuda Cancer Hospital has carried out 5,000 cases of cryosurgery for 34 types of cancer, taking a leading position both at home and abroad.


Principle 

Cryosurgery is an important ablation technique for tumors. The fundamental principle of cryosurgery is as follows. The temperature of cancerous tissue falls to below -160℃rapidly and then raises to normal temperature. The process can lead to dehydration and rupture of cancer cells or destruction of small tumor blood vessels that would lead to tumor cell death. Dead cancerous tissues in situ after cryosurgery can elicits an immunologic reaction as antigens; cancer cells after cryosurgery are more sensitive to chemotherapy or cryosurgery, hence the effectiveness of chemotherapy or radiotherapy is enhanced.

Cryosurgery can be carried out during open surgery, under the guidance of endoscopy or through percutaneous puncture, among percutaneous cryosurgery is most commonly used.
 
 
Advantages

1. Cryosurgery is a localized medical procedure. It can be used as the sole means of cancer treatment or it can be combined with other conventional treatment techniques such as surgical operation, chemotherapy, radiotherapy.

2. Combining cryosurgery with excision can be advantageous since freezing the tumor before excision minimizes the risk of spreading the cancerous cells during excision.

3. In addition to sparing healthy tissue, cryosurgery is advantageous because it is not dose-limited can be repeated as necessary in order to destroy all cancerous tissue.

4. In situations where the tumor is not removed after freezing, especially percutaneous cryosurgery, operative blood loss is small and post-surgical discomfort is minimized.

5. Cryoprobes are relatively small (generally in the range of 24 mm in diameter) and therefore they may be used in minimally invasive surgical procedures.

6. There are no major side effects which are commonly found in chemotherapy or radiotherapy

7. Cryosurgery is adaptable for treatment of tumor close to large vessel which cannot be removed by operation.

8. Cryosurgery can treat small as well as large tumors, and solitary as well as multiple tumors.

9. Cryosurgery not only destroys neoplasms locally, but it also elicits an immunologic reaction (cryoimmunologic reaction) against cancer.

10. It produces a synergy effect to combine cryosurgery with radiotherapy or chemotherapy.

11. There is evidence that the recurrence rate of cancer after cryosurgery is lower than that of operation

Indications:

Nearly all parenchymal cancers are prime candidates for cryoablation. They include liver cancer, ling cancer, kidney cancer, ovarian cancer, pharyngeal cancer, testicular cancer, uterine tumor, vaginal cancer, pancreatic cancer, breast cancer, sarcoma and other benign or malignant lesions of bone, prostate cancer, skin cancer and melanoma, head and neck cancer and soft tissue tumor of various kinds and etc. In addition, cryosurgery can be an effective treatment for retinoblastoma, skin basal cell carcinoma or squamous cell carcinomas, actinic keratosis and cervical intraepithelial neoplasia.

2016年3月30日星期三

The Rank Prize Winner Lu Mingying’s Story of Seeking Treatment at Guangzhou Fuda Cancer Hospital

On March 16, a special patient attended at Guangzhou Fuda Cancer Hospital Press Conference. It’s Chinese British Scientist Dr. Lu Mingying, the Rank Prize winner.

Last month, she accepted nanoknife therapy at Guangzhou Fuda Cancer Hospital, and she was able to walk in the next day.

Dr. Niu Lizhi and Ms. Lu

In the end of 1980s, digital camera was very expensive, which cost several thousand dollars on the international market. Because the imaging sensor used in digital camera was costly at that time. In 1987 and 1989, Wang Guoyu and his wife Lu Mingying joined in experimental group of Edinburgh University in UK. With two professors of Edinburgh University tried to find a new imaging senor. After research, they succeeded in applying common CMOS in imaging sensor. It’s obvious that the innovation brought out so much benefit. The cost of imaging sensor fell by a third, which could put into mass production. Therefore, taking photo with mobile phone also turned to be easy. The cost of camera chip in mobile phone reduced to four dollars dramatically. Phone equipped with camera was not longer luxury but ordinary consumer item. Therefore, they were awarded top prize in the field of science—the Rank Prize. The technique was firstly applied in Nokia mobile phone. “It produces four million camera chips of mobile phones everyday in the world, which is connected with our technique.” Lu Mingying said.

The Rank Prize is one of the top awards in the field of British science, which is regarded as the Nobel Prize in the field of photoelectron and nutrition. The award goes to those who make innovation and contribution to human society in photoelectron and nutrition in the world. Just a few Chinese won this prize, like the Father of Hybrid Rice Yuan Longping and the Father of Optical Fibre Gao Kun.

Lu Mingying felt uncomfortable when she gave lecture at Kunming not long ago, and she was diagnosed as cholangiocarcinoma in local hospital. Her life encountered disaster.

At first, she chose to back Britain for treatment. She once asked help form Prof. Leen of Imperial College Medical School, a world-renowned oncologist specialized at nanoknife ablation therapy.

She could enjoy free treatment in Britain, but she had to wait. And there was no comprehensive therapy at local hospital. Her condition turned worse quickly, so she decided to go to China for treatment.

After transferring to several hospitals, she went to a cancer hospital which just offered chemotherapy and radiation. She didn’t accept chemotherapy. And she went to hospital at Beijing for consultation. They suggested to have chemotherapy firstly, then to have nanoknife therapy. She still didn’t want to have chemotherapy.

She decided to have the new technique -- nanoknife therapy. “I followed the word ‘nanoknife’ and searched in the internet. Finally, I found Guangzhou Fuda Cancer Hospital. I learnt that FUDA have done more than 70 case of nanoknife surgery by several phone consultations. I thought their technique was mature and determined to Guangzhou Fuda Cancer Hospital to have nanoknife ablation therapy.”

President Dr. Niu Lizhi said, “She suffered from abdominal pain and couldn’t walk when she first came to FUDA.”

She first had photodynamic therapy. On February 2, Lu Mingying had nanoknife therapy at Fuda Cancer Hospital. After four day, on February 6, she became better obviously. She could walk and get up to have a photo with President Niu Lizhi in the ward.

Then, she had comprehensive intervention therapy.

A few days ago, in the ward, Lu Mingying’s husband Wang Guoyu told the author that what they appreciated was the advanced technique for cancer treatment around the world, so they chose FUDA. And he disclosed that they were developing more advanced technique of multi-media digital broadcast which would be used in Beijing Road Walking Street.

2016年3月22日星期二

Photodynamic Therapy Shows Magic in Treating Esophageal Cancer Patient

In February 23, 2016, Mr. Wu who is from Inner Mongolia came to Guangzhou Fuda Cancer Hospital for re-examination in company of his son. Learning that the result of re-examination was normal, he hold the hands of his attending doctor Xing Yanli with eyes filling with tears and said, “Doctor Xing, thank you very much. And I also want to thank Doctor Li Hongmei. Thank Fuda Cancer Hospital. There are not only excellent medical skills but also satisfactory service. ”

Mr.Wu(Right)and Doctor Xing’s photo
Mr.Wu is 64 years old, who had been manager of a factory for more than 20 years. He wanted to enjoy the pleasures after retirement. Unexpectedly, he was diagnosed as esophageal cancer with lymph metastasis last year. Mr. Wu’s son was eager to save him and hoped him recover soon. They took Mr. Wu to Beijing for seeking treatment, but the answers all were “surgical removal”. Mr. Wu was afraid of the risk of surgery and hoped to find a mini-invasive treatment plan. His two sons were searching around effective treatments. And they learned that Guangzhou Fuda Cancer Hospital had special cancer treatment mode which met the aspiration of Mr. Wu. Therefore, they decided to have a try at Guangzhou. 

On August 21, 2015, Mr. Wu came to Guangzhou Fuda Cancer Hospital in company of his son. Chief president Xu Kecheng visited him, which made him surprised. Mr. Wu said, “President Xu was so approachable. He joked with me that he was 75 years old which was 11 years older than me, and he also was a cancer patient. I should be confident because they can help. After hearing these words, I felt a load off my mind.”

Learning that Mr.Wu hoped to be treated with mini-invasive treatment, President Xu held a consultation with experts right away. And they decided to adopt photodynamic therapy in treating Mr. Wu.

In fact, there are not a few patients like Mr. Wu who afraid of surgery in clinic. Besides traditional surgery, radiation and chemotherapy, Guangzhou Fuda Cancer Hospital has “3C+P” personalized therapy which including photodynamic therapy. Cancer photodynamic therapy kills cancer cells efficiently by photosensitizer and laser. And it’s mini-invasive treatment.

At the end of August and October, 2015, Mr. Wu accepted esophageal cancer photodynamic therapy twice. On 7 September, he accepted iodine 125 implantation in cardiac lymph nodes. And the surgery was successful. After surgery, Mr. Wu recovered well. Attending Doctor Xing Yanli said, “After having treatments several times, Mr. Wu was better and he just needed to do regular visits.” 

On February 23 of this year, Mr. Wu came back FUDA for re-examination. And all condition was normal. His son said sincerely, “Thank Fuda Cancer Hospital. And I hope Guangzhou Fuda Cancer Hospital can set a branch at Inner Mangolia for the benefit of local patients.” On February 25, Mr. Wu and his son set foot on the way home.
Mr. Wu (R) and his son gave Fuda Cancer Hospital a thumbs-up.


2016年3月2日星期三

Rus’s story Kidney cancer with bone metastasis-Philippines

One year ago, at a seminar in Manila, Philippines, a fifty-year-old lady suddenly came to Prof. Xu Kecheng, her face was familiar, but Prof. Xu could not recall which kind of cancer she had(Figure 9). She said, “Professor Xu, you are my great benefactor, do you think that I am still sick?” I recognized that she was a patient with metastatic renal carcinoma, her name was Rus. Five years ago she had surgery. Three years ago, the patient came to our hospital with bone metastasis. For this kind of progressive renal cancer, chemotherapy and radiotherapy do not work at all. There are ten reports showing that patients with a 5-year survival rate vary from 0-13%. Prof. Xu treated her with Combined Immunotherapy for Cancer (CIC), which she unexpectedly greatly benefited from. Prof. Xu read her latest CT films done in the Philippines and no lesions could be seen. She gave Prof. Xu  two beer bottles with flowers that she herself had painted on as gifts. According to her family's custom, these flowers on beer bottle represent their cordial respects and gratitude. She was afraid Prof. Xu would not accept them, saying that she was too poor to send him valuables, she also did not dare send him valuables as she knew there is a rule in our hospital that all staffs are not allowed to accept gifts from patients. These were not valuables, but a token of her regards, so Prof. Xu accepted. Although Prof. Xu cannot fully understand the true meaning of the painting, he brought back these two beer bottles and put them on the bookcase in his office where he can see them everyday.

On November 19, 2011, the vice president Mr. Binay made an appointment with Prof. Xu in Manila. Mrs. Rus heard that Mr. Binay wanted to meet Prof. Xu, she came to the hotel that he stayed in early that morning, following Prof. Xu to go to the Vice Presidential Palace. Mr. Binay was very excited after listening to Prof. Xu’s presentation and had his photo taken with Mrs. Rus and her sister.

Several years have passed, Rus is still alive and healthy. Every time Professor Xu goes to the Philippines, she always accompanies him, and shares her anti-cancer experience with those cancer patients who still live in great misery.

 
Rus is sharing her personal anti-cancer experience with others

Vice President of the Philippines Binay received Ms. Rus(Left) and her younger sister

Rus is sharing her cancer rehabilitation experience as a volunteer of Fuda


Rus

Kidney cancer with bone metastases

Female, 58 years old, kidney cancer, nephrectomy with recurrent bone metastases.  After she received combined immunotherapy, the metastatic lesion disappeared. She has cancer-free survived for 6 years.

Treatment Experience

Those patients with metastatic kidney cancer who have undergone surgery, chemotherapy and radiotherapy have poor prognosis and their median survival period is less than one year. However, this patient has disease-free survived for 6 years, for which is closely related to immunotherapy.

Cancer cell is heterogeneous, which means cancer gene expression varies and it is very unstable during the differentiation. In other words, cancer cells change day by day. Immunotherapy shall be powerful and adaptable to fight cancer. The immunological measures used shall vary with cancer cells. 

Based on the above understanding, Fuda Cancer Hospital combine a variety of immunological measures, which is so-called combined immunotherapy (CIC), including CIK, DC, T cell transfusion therapy, cytokines injection and non-specific immunostimulating therapy. This would be like fighting a battle, the Army, Navy, Air Force, and even the police (immune cells and cytokines), intelligence agent (DC cells) are indispensable. For immune cells, it shall not only increase their number, but also take measures (non-specific therapy) to stimulate their enthusiasm, so that they dare to make a frontal attack on cancer cells. Of course, in some patients, before they receive one or more immunological measures, some special pre-tests shall be carried out to understand individual differences, on which personalized treatment will be made.

According to Rus’s specific condition, she was recommended to undergo CIC long-term non-specific immune therapy, focusing on mobilizing the initiative of innate anti-cancer ability to inhibit or even eliminate cancer cells (apoptosis), so she manage to obtain long-term survival. It is a great success, which can be called a miracle!

Treatment Team

Xu Kecheng   Professor
Chen Jibing    M.D.
Niu Lizhi    M.D.
Mu Feng    M.D.

Media Reports

Xu Kecheng: Follow Me to Fight Against Cancer,Beijing, People's Medical Publishing House

Videos

Combined Immunotherapy for Cancer