Clemencia Aguinaldo’s story

On December 12, 2015, Ms. Clemencia from Philippine looks great in the khaki’s woolen coat. Before she was discharged, she and her daughter shook hands with Dr. Niu Lizhi, president of Fuda Cancer Hospital in farewell. She said gratefully, “I would like to express my sincere appreciation to Dr. Niu, without whom I might be still tortured by cancer...” Liu Hongyun, head of the nursing group of third ward found it even harder to say goodbye to them. She embraced them tightly and sent her best wishes. The scene was really moving.

A photo of the patient (in the middle) and medical workers

Clemencia is 69 years old this year. She told the reporter that she had always been in good health until July 2010 when she found a mass in the right lower neck. She received examination at a local hospital and was found to have right undifferentiated nasopharyngeal carcinoma. Her condition showed no remission after operation and daily treatment. Later on, a fellow townsman told her that Guangzhou Fuda Cancer Hospital in China has been delivering good therapeutic effects for patients and many people have sought treatment over there. Clemecia decided to give it a try for fear that her condition would aggravate.

In September 2010, she headed for Guangzhou Fuda Cancer Hospital with her daughter. She was surprised to learn that medical workers at FUDA should have arranged airport pick-up service for them. Clemecia said, “FUDA has been very considerate in taking care of foreign patients.”

With the assistance of medical workers at FUDA, Clemencia went through admission formalities in no time. Patient completed relevant examinations after admission. The admitting diagnosis was “multiple solid masses are detected in right neck, which were considered to be enlarged lymph nodes; nasopharyngeal carcinoma with lymph node metastases in right neck; right thyroid nodule.” The expert medical team led by Dr. Niu Lizhi discussed and finalized the treatment plan as argon-helium cryosurgery for her on the basis of the examination result.

Dr. Niu Lizhi introduced that Guangzhou Fuda Cancer Hospital became the first hospital in mainland China to have introduced argon-helium cryosurgery since its initiation in 2001. The biggest advantages of argon-helium cryosurgery lie in its complete destruction of tumor, prevention of tumor metastases, painless treatment process and exemption of body trauma.

Clemencia showed great satisfaction to the treatment plan and her willingness to cooperate with treatment.

On September 15, 2010, Clemencia underwent argon-helium cryosurgery at Guangzhou Fuda Cancer Hospital. She felt much better after the procedure. She also underwent two cycles of interventional chemotherapy on October 12 and November 1 respectively. She showed improved condition and was discharged.

Later, Clemencia underwent another three cycles of interventional chemotherapy at Fuda Cancer Hospital on December 2010, January 2011, and February 2011 respectively.

After she went back to Philippine, Clemencia received many times of examinations at local hospital and no evidence of tumor recurrence was ever found. Some of her friends were so surprised to see her in such good condition, saying, “You look so energetic and doesn’t look like a cancer patient at all”. Clemencia was really glad to hear that. She said her condition has improved significantly and she is totally fit after treatment at Fuda Cancer Hospital.

In December 2015, Clemencia come back to FUDA once again for re-examination and DC-CIK immunotherapy. She told the reporter that she now has good quality of sleep and good spirit every day. And she has resumed her living habit before she got sick. She takes a walk every day as walking is her favorite sport. She once again expressed her thanks to medical workers at FUDA for helping her regain a healthy life.

A photo of (from left to right) the patient’s daughter, the patient, Liu Hongyun, head of the nursing group of third ward, the patient’s husband (during hospitalization) 

A photo of (from left to right) the patient, patient’s daughter, Liu Hongyun, head of the nursing group of third ward on December 12, 2015

A photo of (from Left to right) the patient, patient’s daughter, Liu Hongyun, head of nursing group of third ward on December 12, 2015

TIPS：

Cryosurgical Ablation (CSA)

As a new treatment for cancer, cryosurgery has been approved by the United States FDA (Food and Drug Administration in 1998 and China FDA in 1999 respectively. China has been taking a lead in the world both in terms of cryosurgery cases and treated types of cancer. Since the introduction of cryosurgery in 2000, Fuda Cancer Hospital has carried out 5,000 cases of cryosurgery for 34 types of cancer, taking a leading position both at home and abroad.

Principle 

Cryosurgery is an important ablation technique for tumors. The fundamental principle of cryosurgery is as follows. The temperature of cancerous tissue falls to below -160℃rapidly and then raises to normal temperature. The process can lead to dehydration and rupture of cancer cells or destruction of small tumor blood vessels that would lead to tumor cell death. Dead cancerous tissues in situ after cryosurgery can elicits an immunologic reaction as antigens; cancer cells after cryosurgery are more sensitive to chemotherapy or cryosurgery, hence the effectiveness of chemotherapy or radiotherapy is enhanced.

Cryosurgery can be carried out during open surgery, under the guidance of endoscopy or through percutaneous puncture, among percutaneous cryosurgery is most commonly used.

 
 

Advantages

1. Cryosurgery is a localized medical procedure. It can be used as the sole means of cancer treatment or it can be combined with other conventional treatment techniques such as surgical operation, chemotherapy, radiotherapy.

2. Combining cryosurgery with excision can be advantageous since freezing the tumor before excision minimizes the risk of spreading the cancerous cells during excision.

3. In addition to sparing healthy tissue, cryosurgery is advantageous because it is not dose-limited can be repeated as necessary in order to destroy all cancerous tissue.

4. In situations where the tumor is not removed after freezing, especially percutaneous cryosurgery, operative blood loss is small and post-surgical discomfort is minimized.

5. Cryoprobes are relatively small (generally in the range of 24 mm in diameter) and therefore they may be used in minimally invasive surgical procedures.

6. There are no major side effects which are commonly found in chemotherapy or radiotherapy

7. Cryosurgery is adaptable for treatment of tumor close to large vessel which cannot be removed by operation.

8. Cryosurgery can treat small as well as large tumors, and solitary as well as multiple tumors.

9. Cryosurgery not only destroys neoplasms locally, but it also elicits an immunologic reaction (cryoimmunologic reaction) against cancer.

10. It produces a synergy effect to combine cryosurgery with radiotherapy or chemotherapy.

11. There is evidence that the recurrence rate of cancer after cryosurgery is lower than that of operation

Indications:

Nearly all parenchymal cancers are prime candidates for cryoablation. They include liver cancer, ling cancer, kidney cancer, ovarian cancer, pharyngeal cancer, testicular cancer, uterine tumor, vaginal cancer, pancreatic cancer, breast cancer, sarcoma and other benign or malignant lesions of bone, prostate cancer, skin cancer and melanoma, head and neck cancer and soft tissue tumor of various kinds and etc. In addition, cryosurgery can be an effective treatment for retinoblastoma, skin basal cell carcinoma or squamous cell carcinomas, actinic keratosis and cervical intraepithelial neoplasia.

Laureate of Rank Prize commented that you can entrust your life to Fuda Cancer Hospital

On March 24, 2016, Ms. Lu Mingying, a renowned scientist and Rank Prize laureate was discharged from hospital after receiving comprehensive treatment at Fuda Cancer Hospital for two months. One day before discharge, she put on her scarf and, to express her joy and appreciation, she said good-bye to doctors and nurses who had been taking care of her express “It is the doctors at FUDA that have saved me from the verge of death.” 
 

Xu Kecheng, Chief President of Fuda Cancer Hospital and Ms. Lu Mingying

 

Ms. Lu Mingying and nurses of the 4th ward

One week before her discharge, we visited her. During the interview, she worn the same red scarf. “This is a present from a friend of mine cause wearing red makes me look more radiant.” She felt much betteras she just stooped her oral chemotherapy medicine on that day. She shared with us her experience of studying in UK, her Rank Prize winning stories and her journey of fighting against cancer.

The influence of her father  

Lu Mingying was born in a scholarly family in 1954. Her father Lu Zhongzuo, the founder of vacuum electronic devices major in China, had long engaged in the research of microwave tube and wrote the first batch of textbooks and monographs on microwave electronics in China. “Being raised in such an environment, I developed a keen interest in mathematics, physics and optoelectronics since I was a little child.”she said. Unfortunately, she had to suspend her schooling as the Great Cultural Revolution broke out when she was just enrolled into middle school. Two years later, she resumed her schooling in a nearby middle school. In 1970, Lu Mingying, who just turned to 16, was assigned to a small factory and worked there for seven years.

Lu Mingqi, Lu Ming’s elder sister, noted, “Before the college entrance examination system was resumed in China, my sister had never quit learning. She worked during the day and studied at night”. It was with her persistence that she made her way into the Department of Electronic Engineering of Nanjing Institute of Technology (currently Southeast University) in 1977.  

Lu Mingying (R) and her elder sister Lu Mingqi

In university, Lu Mingying met her life partner - Wang Guoyu, her classmate. In her memory, they spent most of time doing research in the lab instead of going dating. Upon graduation from university, Lu Mingying was accepted into the postgraduate program of Southeast University while Wang Guoyu was accepted into the postgraduate program of Tsinghua University. They got married after finished their master degree. In 1984, they had their fist child. Later, Lu Mingying served as a lecturer in Southeast University while her husband also chose to work as lecturer in the same university.

Studying in England 

In the end of 1980s, digital camera was very expensive and it cost thousands of dollars to buy one. The main reason was that the imaging sensor of digital camera was very costly. Even researchers in Japan, Europe and America were not able to tackle the difficult problem.

Wang Guoyu and Lu Mingying, who were then studied in the University of Edinburgh, were enrolled into an experimental group in 1987 and 1989 respectively. They joined two professors of the University of Edinburgh with a clear purpose, that was to develop new imaging sensors. They put forward a bold proposal, which was whether common semiconductor integrated circuit can be applied to imaging sensor as it can greatly reduce the cost of imaging sensor.

After years of unremitting efforts, they successfully applied common semiconductor integrated circuit into imaging sensor. The technological innovation has brought about great changes. The cost of imaging sensor reduced by one third; imaging sensor can be mass produced; the price of digital camera fell from several thousands dollars to around 10 USD. In 2002, the technology began to be applied to Nokia mobile phones and widely has been applied to mobile phones since then. Mobile phone photographing has become an easy thing. It has turned from a luxury to popular consumable goods. “The 50million chips for mobile phone photographing produced every day are using our technology.” Lu Mingying said proudly.

A surprising award

The application of common semiconductor integrated circuit in imaging sensors is an epoch-making shift in the industry of digital camera. The four researchers including Lu Mingying were awarded the Rank Prize in 2008.

Established in 1972, the Rank Prize is one of the top science awards in England in recognition of researchers who have made tremendous contribution to the fields of optoelectronic science and nutriology. It is reputed as the Nobel Prize in the fields of optoelectronic science and nutriology. As of now, only a few Chinese, including Charles Kao, the Father of Fiber Optic Communications and Yuan Longping, the Father of Hybrid Rice, have won the Rank Prize.

“It’s really surprising”, Lu Mingying said when she delivered her acceptance speech. It turned out that in March 2007, Lu Mingying received a letter, asking if she would like to participate in the selection of the Rank Prize. “The scientific research achievement was made over 10 years ago. We almost forget about it.” The couple felt that it must be someone who was playing tricks with them so they did not pay any attention to it. Shortly after that, Lu Mingying received a letter from her previous supervisor, asking if she had received an invitation letter for the selection of the Rank Prize. It was until then did the couple realized that it was not a trick.

“I was so surprised and excited”, said Lu Mingying. They had invested so much time and efforts in order to overcome the technical difficulty. It was really a surprise for them to finally get the recognition after over 10 years. 

Facing up to the devil of cancer

In December, 2015, Lu Mingying started to feeling unwell and often had lower abdomen pain. She had thought it was just urinary system infection and took a lot of antibiotics but the symptoms showed no remission. In December, she come to China for an academic conference. Her husband insisted that she should do a  physical examination. Ultrasound result showed that there was a tumor sizing 7x8cm in liver. The doctor said that she was at advanced stage and an immediate CT scan was suggested. Further examinations proved that she was suffering from cholangiocarcinoma with metastases in bones, lymph nodes and abdominal cavity.

“It was the first time I’ve heard of this term and I had no idea what it is exactly. I searched on the Internet and learned that cholangiocarcinoma cannot be easily treated.” In the face of the unexpected disease, Lu Mingying did nor show extreme sadness and despair as other cancer patients. She did not She was so emotionally peaceful when she was telling us her story.

Some doctors suggested her to do radiotherapy and chemotherapy first but she declined. She kept on looking for new and mini-invasive treatments on the internet. One day, she accidentally read a piece of news, saying that cholangiocarcinoma can be treated with NanoKnife. “I saw a light of hope after I read the news”. At first, she chose to go back to England for treatment. She consulted a renowned Nanoknife specialist from the Medical School of Imperial College London. However, it would take long time waiting for NanoKnife in England. She chose to go back to China for NanoKnife for fear that her condition would progress. 

Getting to know FUDA by virtue of NanoKnife  
  
Lu Mingying set her mind on the new technology of NanoKnife. She searched about NanoKnife on the Internet and finally traced down to Guangzhou Fuda Cancer Hospital. After learned that FUDA had completed over 70 cases of NanoKnife, she decided to come to Guangzhou Fuda Cancer Hospital for treatment. 

Her sister said, “Before we come to FUDA, I went all the way to a major hospital in Xi’an cause I read from a newspaper that the hospital has completed successful cases of NanoKnife. I even consulted a specialist about my sister’s case but the specialist said the tumor was too big to be ablated. ”

In January 13, 2016, Lu Mingying was admitted into Fuda Cancer Hospital. Due to rapid disease progression, she was too weak to walk upon admission and she had ascites and fever. “From the first day that I was admitted into the hospital, I have had the feeling that it was right for me to choose FUDA. All medical staffs, from the president to doctors and nurses have been very nice to me. On the second day of my admission, Xu Kecheng, the Chief President of FUDA, Niu Lizhi, the Executive President of FUDA and other experts made rounds and they gave me a lot of encouragement. I felt assured. I’mconvinced that I could entrust my life to FUDA. If FUDA cannot do any treatment for me, I won’t be treated in anywhere else.”

In the following days, Lu Mingying received comprehensive treatments, including photodynamic therapy, NanoKnife, iodine seeds implantation therapy, etc. “It is the doctors at FUDA that have saved me from the verge of death.” Lu Mingying said. 

After two months’ treatments, she has built up more and more confidence in FUDA. Where does the confidence come from? First of all, it comes from the excellent skills of the doctors. They have been very patient in explaining to me the upcoming treatment and I’m very clear about the possible side effects; secondly, it comes from the “green therapy” offered by FUDA. The green therapy, or minimally invasive treatment, has inflicted no pain, which accords with my concept of treatment; thirdly, the confidence comes from the humanitarian service provided by FUDA. Doctors, nurses and cleaners always greet patients with smile. I have been feeling very comfortable for the last two months.

“One of my supervisors died of brain cancer. I thought how nice it would be if he had been treated at FUDA. That’s why I want to share my treatment experience and feelings with other patients so that more patients can get to know FUDA and gain survival benefits here. ”

The Rank Prize Winner Lu Mingying’s Story of Seeking Treatment at Guangzhou Fuda Cancer Hospital

On March 16, a special patient attended at Guangzhou Fuda Cancer Hospital Press Conference. It’s Chinese British Scientist Dr. Lu Mingying, the Rank Prize winner.

Last month, she accepted nanoknife therapy at Guangzhou Fuda Cancer Hospital, and she was able to walk in the next day.

Dr. Niu Lizhi and Ms. Lu

In the end of 1980s, digital camera was very expensive, which cost several thousand dollars on the international market. Because the imaging sensor used in digital camera was costly at that time. In 1987 and 1989, Wang Guoyu and his wife Lu Mingying joined in experimental group of Edinburgh University in UK. With two professors of Edinburgh University tried to find a new imaging senor. After research, they succeeded in applying common CMOS in imaging sensor. It’s obvious that the innovation brought out so much benefit. The cost of imaging sensor fell by a third, which could put into mass production. Therefore, taking photo with mobile phone also turned to be easy. The cost of camera chip in mobile phone reduced to four dollars dramatically. Phone equipped with camera was not longer luxury but ordinary consumer item. Therefore, they were awarded top prize in the field of science—the Rank Prize. The technique was firstly applied in Nokia mobile phone. “It produces four million camera chips of mobile phones everyday in the world, which is connected with our technique.” Lu Mingying said.

The Rank Prize is one of the top awards in the field of British science, which is regarded as the Nobel Prize in the field of photoelectron and nutrition. The award goes to those who make innovation and contribution to human society in photoelectron and nutrition in the world. Just a few Chinese won this prize, like the Father of Hybrid Rice Yuan Longping and the Father of Optical Fibre Gao Kun.

Lu Mingying felt uncomfortable when she gave lecture at Kunming not long ago, and she was diagnosed as cholangiocarcinoma in local hospital. Her life encountered disaster.

At first, she chose to back Britain for treatment. She once asked help form Prof. Leen of Imperial College Medical School, a world-renowned oncologist specialized at nanoknife ablation therapy.

She could enjoy free treatment in Britain, but she had to wait. And there was no comprehensive therapy at local hospital. Her condition turned worse quickly, so she decided to go to China for treatment.

After transferring to several hospitals, she went to a cancer hospital which just offered chemotherapy and radiation. She didn’t accept chemotherapy. And she went to hospital at Beijing for consultation. They suggested to have chemotherapy firstly, then to have nanoknife therapy. She still didn’t want to have chemotherapy.

She decided to have the new technique -- nanoknife therapy. “I followed the word ‘nanoknife’ and searched in the internet. Finally, I found Guangzhou Fuda Cancer Hospital. I learnt that FUDA have done more than 70 case of nanoknife surgery by several phone consultations. I thought their technique was mature and determined to Guangzhou Fuda Cancer Hospital to have nanoknife ablation therapy.”

President Dr. Niu Lizhi said, “She suffered from abdominal pain and couldn’t walk when she first came to FUDA.”

She first had photodynamic therapy. On February 2, Lu Mingying had nanoknife therapy at Fuda Cancer Hospital. After four day, on February 6, she became better obviously. She could walk and get up to have a photo with President Niu Lizhi in the ward.

Then, she had comprehensive intervention therapy.

A few days ago, in the ward, Lu Mingying’s husband Wang Guoyu told the author that what they appreciated was the advanced technique for cancer treatment around the world, so they chose FUDA. And he disclosed that they were developing more advanced technique of multi-media digital broadcast which would be used in Beijing Road Walking Street.

Photodynamic Therapy Shows Magic in Treating Esophageal Cancer Patient

In February 23, 2016, Mr. Wu who is from Inner Mongolia came to Guangzhou Fuda Cancer Hospital for re-examination in company of his son. Learning that the result of re-examination was normal, he hold the hands of his attending doctor Xing Yanli with eyes filling with tears and said, “Doctor Xing, thank you very much. And I also want to thank Doctor Li Hongmei. Thank Fuda Cancer Hospital. There are not only excellent medical skills but also satisfactory service. ”

Mr.Wu(Right)and Doctor Xing’s photo

Mr.Wu is 64 years old, who had been manager of a factory for more than 20 years. He wanted to enjoy the pleasures after retirement. Unexpectedly, he was diagnosed as esophageal cancer with lymph metastasis last year. Mr. Wu’s son was eager to save him and hoped him recover soon. They took Mr. Wu to Beijing for seeking treatment, but the answers all were “surgical removal”. Mr. Wu was afraid of the risk of surgery and hoped to find a mini-invasive treatment plan. His two sons were searching around effective treatments. And they learned that Guangzhou Fuda Cancer Hospital had special cancer treatment mode which met the aspiration of Mr. Wu. Therefore, they decided to have a try at Guangzhou. 

On August 21, 2015, Mr. Wu came to Guangzhou Fuda Cancer Hospital in company of his son. Chief president Xu Kecheng visited him, which made him surprised. Mr. Wu said, “President Xu was so approachable. He joked with me that he was 75 years old which was 11 years older than me, and he also was a cancer patient. I should be confident because they can help. After hearing these words, I felt a load off my mind.”

Learning that Mr.Wu hoped to be treated with mini-invasive treatment, President Xu held a consultation with experts right away. And they decided to adopt photodynamic therapy in treating Mr. Wu.

In fact, there are not a few patients like Mr. Wu who afraid of surgery in clinic. Besides traditional surgery, radiation and chemotherapy, Guangzhou Fuda Cancer Hospital has “3C+P” personalized therapy which including photodynamic therapy. Cancer photodynamic therapy kills cancer cells efficiently by photosensitizer and laser. And it’s mini-invasive treatment.

At the end of August and October, 2015, Mr. Wu accepted esophageal cancer photodynamic therapy twice. On 7 September, he accepted iodine 125 implantation in cardiac lymph nodes. And the surgery was successful. After surgery, Mr. Wu recovered well. Attending Doctor Xing Yanli said, “After having treatments several times, Mr. Wu was better and he just needed to do regular visits.” 

On February 23 of this year, Mr. Wu came back FUDA for re-examination. And all condition was normal. His son said sincerely, “Thank Fuda Cancer Hospital. And I hope Guangzhou Fuda Cancer Hospital can set a branch at Inner Mangolia for the benefit of local patients.” On February 25, Mr. Wu and his son set foot on the way home.

Mr. Wu (R) and his son gave Fuda Cancer Hospital a thumbs-up.

Pancreatic Cancer Patient’s Life Being Rescued by Nanoknife Therapy at Guangzhou Fuda Cancer Hospital

On 29th February 2016, sunshine drove away the gloomy and the dark. After having nanoknife (irreversible electroporation) therapy, Mr. Qiu was going to leave hospital with heat full of hope. Looking back on the eight months of fighting against carcinoma of pancreatic head, he was filled with emotion. When Xu Kecheng, chief president of Guangzhou Fuda Cancer Hospital visited him, Mr. Qiu said sincerely: Thank you for making me not afraid of cancer anymore. I am confident to get back to health, because I receive correct treatment here.
 

Chief president Xu Kecheng (left) was visiting Mr. Qiu.


Mr. Qiu was thanking Doctor Shi Hongxia (middle).
 

Confront with carcinoma of pancreatic head
 

Mr. Qiu comes from Hong Kong. He is a 65-year old man with a pair gleaming eyes. He sat in front of me with a smile on his face. No one will think he is a cancer patient who has held on to fight against carcinoma of pancreatic head for 2800 days and nights.

Dr. Niu Lizhi, president of Guangzhou Fuda Cancer Hospital said that carcinoma of pancreatic head is malignant tumor. Eight months ago, Mr. Qiu was overwhelmed with sadness by the diagnosis.

Mr. Qiu once worked for a grand theatre. He has a filial daughter. He should have enjoyed the happiness of family. Unfortunately, on July 2015, Mr. Qiu found himself becoming thin and losing 10 kilograms without cause while suffering from abdominal pain. Mr. Qiu didn’t pay attention on it. After two months, he had diarrhea three to five times a day on average. On 11th November, he went to local hospital for examination without company of family.

After examination, Mr. Qiu was diagnosed as carcinoma of pancreatic head. PET-CT shown that was a 6.5 cm * 4.4 cm lump. Mr. Qiu said, he was so sad and shocked for knowing that carcinoma of pancreatic head is hard to treat, which made him felt death was approaching him.

Doctor of Hong Kong thought it took big risks having whipple surgery (pancreas duodenectomy) and advised Mr. Qiu to take biliary stent and bypass surgery. But Mr. Qiu refused. After taking chemotherapy twice, abdomen MRI scan showed the lump on pancreatic head reduced to 4.6 cm *3.9 cm. However, after having chemotherapy, he developed red rushes, itching, myelosuppression and hair loss etc. Chemotherapy was so painful that Mr. Qiu was urgent to find a suitable treatment plan.

I found proper treatment here luckily.

“Fortunately, when I failed in seeking treatment, my daughter took part in the lecture delivered by Mufeng, vice president of Guangzhou Fuda Cancer Hospital. She learnt about the most advanced ablation technique nanoknife therapy (irreversible electroporation) which can ablate targeted tumors and apply to pancreatic cancer. My intuition told me that Guangzhou Fuda Cancer Hospital will be my savior.”

On 17th February, Mr. Qiu was admitted to Guangzhou Fuda Cancer Hospital with being diagnosed as cT4N1M0 stage Ⅲ of carcinoma of pancreatic head. Soon, president Niu made a rigorous treatment plan for Mr. Qiu. It’s irreversible electroporation (nanoknife therapy) for carcinoma of pancreatic head treatment. On 23rd February, the operation was conducted smoothly and patient’s blood loss was just 2ml.

For more understanding of Guangzhou Fuda Cancer Hospital and the successful completion of nanoknife surgery, Mr. Qiu began to see hope. Remind of the period of having chemotherapy, I was often weak and tired at that time. But after nanoknife surgery, my psychological condition became better, and I became happier gradually. Mr. Qiu’s daughter said: “After nanoknife surgery, my father was better obviously. His psychological condition was improved. The confidence and encouragement of fighting against cancer were boosted.”

Mr. Qiu said, it’s unfortunate to have carcinoma of pancreatic head, but I was lucky to have advanced nanoknife therapy with good therapeutic effects in the fight against cancer. And he was said emotionally: “I sincerely appreciate Guangzhou Fuda Cancer Hospital. Thanks Dr. Niu Lizhi for performing operation for me. I also want to thank Doctor Shi Hongxia and nurses. The medical condition and environment are satisfactory and comfortable.”

In the afternoon of 29th February, chief president Xu Kecheng, Doctor Shi Hongxia and other medical workers visited Mr. Chou for he was going to leave. He expressed his gratitude again: I will come to have re-examination. It’s you who teach me to never give up at any time.
 

Photo of Mr. Qiu (middle), President Niu Lizhi (No.3 from right) and treatment team

Rus’s story Kidney cancer with bone metastasis-Philippines

One year ago, at a seminar in Manila, Philippines, a fifty-year-old lady suddenly came to Prof. Xu Kecheng, her face was familiar, but Prof. Xu could not recall which kind of cancer she had(Figure 9). She said, “Professor Xu, you are my great benefactor, do you think that I am still sick?” I recognized that she was a patient with metastatic renal carcinoma, her name was Rus. Five years ago she had surgery. Three years ago, the patient came to our hospital with bone metastasis. For this kind of progressive renal cancer, chemotherapy and radiotherapy do not work at all. There are ten reports showing that patients with a 5-year survival rate vary from 0-13%. Prof. Xu treated her with Combined Immunotherapy for Cancer (CIC), which she unexpectedly greatly benefited from. Prof. Xu read her latest CT films done in the Philippines and no lesions could be seen. She gave Prof. Xu  two beer bottles with flowers that she herself had painted on as gifts. According to her family's custom, these flowers on beer bottle represent their cordial respects and gratitude. She was afraid Prof. Xu would not accept them, saying that she was too poor to send him valuables, she also did not dare send him valuables as she knew there is a rule in our hospital that all staffs are not allowed to accept gifts from patients. These were not valuables, but a token of her regards, so Prof. Xu accepted. Although Prof. Xu cannot fully understand the true meaning of the painting, he brought back these two beer bottles and put them on the bookcase in his office where he can see them everyday.

On November 19, 2011, the vice president Mr. Binay made an appointment with Prof. Xu in Manila. Mrs. Rus heard that Mr. Binay wanted to meet Prof. Xu, she came to the hotel that he stayed in early that morning, following Prof. Xu to go to the Vice Presidential Palace. Mr. Binay was very excited after listening to Prof. Xu’s presentation and had his photo taken with Mrs. Rus and her sister.

Several years have passed, Rus is still alive and healthy. Every time Professor Xu goes to the Philippines, she always accompanies him, and shares her anti-cancer experience with those cancer patients who still live in great misery.

 

Rus is sharing her personal anti-cancer experience with others

Vice President of the Philippines Binay received Ms. Rus(Left) and her younger sister

Rus is sharing her cancer rehabilitation experience as a volunteer of Fuda

Rus

Kidney cancer with bone metastases

Female, 58 years old, kidney cancer, nephrectomy with recurrent bone metastases.  After she received combined immunotherapy, the metastatic lesion disappeared. She has cancer-free survived for 6 years.

Treatment Experience

Those patients with metastatic kidney cancer who have undergone surgery, chemotherapy and radiotherapy have poor prognosis and their median survival period is less than one year. However, this patient has disease-free survived for 6 years, for which is closely related to immunotherapy.

Cancer cell is heterogeneous, which means cancer gene expression varies and it is very unstable during the differentiation. In other words, cancer cells change day by day. Immunotherapy shall be powerful and adaptable to fight cancer. The immunological measures used shall vary with cancer cells. 

Based on the above understanding, Fuda Cancer Hospital combine a variety of immunological measures, which is so-called combined immunotherapy (CIC), including CIK, DC, T cell transfusion therapy, cytokines injection and non-specific immunostimulating therapy. This would be like fighting a battle, the Army, Navy, Air Force, and even the police (immune cells and cytokines), intelligence agent (DC cells) are indispensable. For immune cells, it shall not only increase their number, but also take measures (non-specific therapy) to stimulate their enthusiasm, so that they dare to make a frontal attack on cancer cells. Of course, in some patients, before they receive one or more immunological measures, some special pre-tests shall be carried out to understand individual differences, on which personalized treatment will be made.

According to Rus’s specific condition, she was recommended to undergo CIC long-term non-specific immune therapy, focusing on mobilizing the initiative of innate anti-cancer ability to inhibit or even eliminate cancer cells (apoptosis), so she manage to obtain long-term survival. It is a great success, which can be called a miracle!

Treatment Team

Xu Kecheng   Professor

Chen Jibing    M.D.

Niu Lizhi    M.D.

Mu Feng    M.D.

Media Reports

Xu Kecheng: Follow Me to Fight Against Cancer，Beijing, People's Medical Publishing House

Videos

Combined Immunotherapy for Cancer

Ms. Xu's Story

On December 27, 2015, Madam Xu, a pancreatic cancer patient from Shanghai was discharged as her condition has improved after received meticulous treatment at FUDA. The daughter of Madam Xu said with great relief, “Seeing that my mom has improved both mentally and physically, I would like to express my deep appreciation to Dr. Niu Lizhi and Guangzhou Fuda Cancer Hospital.”

President Xu visiting Madam Xu

In mid June, 2015, Madam Xu had intermittent dull pain in upper abdomen and aversion to greasy food. On June 30, she had yellowing in whole body skin and in sclera and was hospitalized in a local hospital. The impressions of CT scan were as follows: a space-occupying lesion about 3cmx2cm in size is detected in the neck of pancreas and is found to have invaded lower segment of common bile duct; intrahepatic and extrahepatic bile ducts dilation is detected; an abnormal  enhancing lesion is found in outer right lobe of liver. The attending doctor suggested operation but Madam Xu declined and just took traditional Chinese medicine for anti-cancer treatment. 

In October, Madam Xu had aggravated symptoms, including intermittent abdominal pain, vomiting after food intake, difficult defecation and etc. To seek further treatment, Madam Xu was hospitalized at Guangzhou Fuda Cancer Hospital in the company of her family members on November 6.

A photo of Dr. Niu Lizhi and Madam Xu

After she was hospitalized into FUDA, Dr. Niu arranged whole-body examinations for her in no time. After learned that Madam Xu has nutrition risk as she had 15kg of body weight loss since her illness, the attending doctor prescribed nutrition support for her.

To further control tumor progression, the medical team decided to perform NanoKnife therapy for her. On November 10, the NanoKnife therapy medical team headed by Dr. Niu Lizhi performed irreversible electroporation (NanoKnife therapy) under the guidance of B ultrasound for Madam Xu as scheduled, two electron-probes were punctured into the tumor in the neck of pancreas for local ablation. The procedure went smoothly. The volume of bleeding was only 50ml during the procedure.

After the procedure, Madam Xu has had a good recovery. She has resumed her good spirit and appetite to some extent and she has also gained some weight. On December 10, the doctor attending to madam Xu arranged immuntherapy for her in order to boost her own anti-cancer immunity. Seeing that her mother’s condition had significant improvement, Madam Xu’s daughter was greatly relieved. She told the writer that they have came all the way from Shanghai to Guangzhou Fuda Cancer Hospital for NanoKnife therapy. “I learned on the Internet that Fuda Cancer Hospital has successfully carried out the first case of Nanoknife therapy for pancreatic cancer in mainland China”. That’s why I decided to bring my mother to FUDA and have a try. The treatment has delivered good curative effects exactly as we have expected.”

According to statistics, the NanoKnife therapy medial team led by Dr. Niu Lizhi has saved over 60 pancreatic cancer patients from the verge of death. We believe that more and more cancer patients will receive benefit from the latest technology in the future.

TIPS: Seven advantages of NanoKnife therapy

Dr. Niu Lizhi indicated that NanoKnife therapy is a safe and highly effective minimally-invasive technology for tumor treatment. Compared with other tumor treatment method, it has the following advantages:

1. Short ablation duration

For solid tumors about 3 cm in diameter, it requires just 90x100milisecond ultrashort pulses. One group of treatment takes less than one minute. Even if there are 3 to 4 overlapped ablation areas, the whole ablation duration will be less than 5 minutes.

2. Preserving important tissues such as vessels and nerves in ablated areas

Nanoknife therapy can protect important tissue structures in ablated areas. Important liver structures, such as hepatic artery, hepatic vein, portal vein and intrahepatic bile ducts can be well protected after being treated with Nanoknife therapy.

3. No heat island effect

Nanoknife System for tumor ablation uses electrical pulses to breakdown cell membrane. The procedure will neither generate energy nor be influenced by external temperature.
4. Thorough ablation with clear demarcation
IRE can perform thorough ablation to tumor regardless of its site, size and shape even if it’s tumors close to vessels or tumor with irregular shape or big size. Moreover, there is a demarcation between ablated area and non-ablated area; therefore, more precise judgment and evaluation can be made for the follow-up, effectiveness and treatment performance of Nanoknife Therapy. Moreover, NanoKnife therapy can exempt the possibility of tumor recurrence after treatment.

5. Ablated area will remain functional

Different from conventional ablation modes, Nanoknife therapy can promote cell death through immunity stimulation. Human body will identify cell apoptosis as normal cell death and then clean apoptotic tissue through cytophagy so as to promote the regeneration and repair of normal tissue.

6. Real time monitoring during treatment

Nanoknife Therapy can be navigated and monitored by ultrasound, CT or MRI. There is only few millimeters of difference in size between ablated areas monitored by ultrasound or CT and that measured in pathological analysis. The imaging can also clearly display unablated residual cancer cells, to which doctors can perform ablation again. Moreover, real time monitoring allows doctors to observe the changes in the surrounding tissues of ablated area and predict the possibility of complications so as to guarantee patient’s safety and quick postoperative recovery.

7. Nanoknife Therapy can be applied to more complicated conditions

As NanoKnife therapy inflicts no injury to such important tissues. It could deliver safe and effective treatment for the tumor which is close to big vessels, bile duct, pancreatic duct and hepatic portal vein, prostate cancer and cancer close to spine.